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Figure 5 | Veterinary Research

Figure 5

From: A live attenuated Salmonella Enteritidis secreting detoxified heat labile toxin enhances mucosal immunity and confers protection against wild-type challenge in chickens

Figure 5

Recovery of challenge strain from internal organs of chickens. Enumeration of wild type bacterial load was performed in liver, spleen, and cecum of the bird after virulent wild type challenge. (A) Log10 organ bacterial counts of bird groups immunized orally, at the 7th day post-challenge. Spleens from Group C showed significant reduction in challenge bacterial load as compared to Group A and B (P ≤ 0.05) birds. (B) Log10 organ bacterial counts of bird groups immunized intramuscularly, at the 7th day post-challenge. The splenic bacterial loads were significantly lower in Group B and C as compared to Group A (P ≤ 0.05). The caecal bacterial load was significantly lower in Group C, birds immunized with adjuvanted strain (P ≤ 0.05). (C) Log10 organ bacterial counts of bird groups immunized orally, at the 14th day post-challenge. Spleens and ceca of Group B and C showed significant decreased in bacterial loads as compared to the control group A (P ≤ 0.05). (D) Log10 organ bacterial counts of bird groups immunized intramuscularly, at the 14th day post-challenge. In Group B and C, the number of birds determined to be completely negative of the challenge strain were 4 of 10.

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