The C-terminal domain of Clostridium perfringens alpha toxin as a vaccine candidate against bovine necrohemorrhagic enteritis

Table 1 Clostridium perfringens strains used in the study

Strain^a	Strain number	Phenotype	Origin	Toxin genes	Alpha toxin (*10⁻³ U/mL) mean ± SEM	Ref.
Wild-type	JIR325	Wild-type	Strain 13^b	plc	31.392 ± 0.079	[16]
∆plc	JIR4107	Alpha toxin-deficient	JIR325 Δplc		<0.8	[17]
∆plc (shuttle vector)	JIR4120	Alpha toxin-deficient with shuttle vector	JIR4107(pJIR418)		<0.8	[17]
complemented	JIR4121	Alpha toxin- complemented	JIR4107(pJIR443)	plc	28.32 ± 0.38	[17]

^a plc: alpha toxin gene.
^bJIR325: a rifampicin and nalidixic acid-resistant derivative of strain 13, a C. perfringens strain originally isolated from soil.

ISSN: 1297-9716