Figure 5

Offspring from buparvaquone treated dams had a higher survival rate as offspring from placebo treated dams. Survival curves of pups during 30 days pp of buparvaquone-treated (BPQ, solid line) and corn oil (Placebo, dashed line) treated dams, both of which were infected with Nc-Spain7 isolate of N. caninum. As a parameter for survival, the Kaplan–Meier-estimator (KME) is shown. The differences of BPQ and placebo survival curves were highly significant (log-rank-test; p < 10⁻¹²). In the untreated group (No treat.), no pup died (dotted line).