Parasite load in brains and lungs of mice treated with artemiside, artemisone, or mefloquine. Male BALB/c mice were infected with Nc-Spain7 tachyzoites and subsequently treated with artemiside (ARI), artemisone (ARO), mefloquine (MEF) in corn oil or corn oil only (Placebo) as detailed in Section “Materials and methods”. The mice were euthanized 3 weeks pi. After euthanasia, brains and lungs were collected and the amount of tachyzoites was determined by quantitative PCR and are presented as box plots (n = 6). A brains, B lungs.