Figure 1

Lesion development over a 6 week period post-infestation with P. ovis across repeated vaccine trials. Lambs were infested with ~50 mites following immunisation with a seven recombinant protein cocktail vaccine with QuilA adjuvant (vaccine) or adjuvant only (control). Data on lesion size are presented on the transformed scale (cm, square root of lesion size). The plot shows observed lesion size of each lamb of vaccine (triangles) and control (circles) groups, estimated mean lesion size of vaccine (solid line) and control (dashed line) groups and corresponding 95% CIs envelop (shaded region).