Immunohistochemical detection of PrP
in peripheral tissues.
A Intrapancreatic ganglia neurons showing perineuronal (*) and granular intracytoplasmic labeling (arrow). C Adrenal gland showing granular deposits in ganglionic neurons (red circle) and chromaffin cells (arrow). E Sh-BSE kidney showing PrPSc deposits in tubular structure (arrow head). B, D, E Absence of a detectable positive signal in corresponding tissues from the control pig.