Figure 3
From: Transmission of sheep-bovine spongiform encephalopathy to pigs
Photomicrographs of retinal cross-sections from negative control (A, C) and clinically affected pigs (B, D). All layers of the control retina (A) show normal organization and cytoarchitecture. GCL ganglion cell layer, IPL inner plexiform layer, INL inner nuclear layer, OPL outer plexiform layer, ONL outer nuclear layer, PS photoreceptor segments. B Moderate disorganization and decreased cellular density is observed within the INL and ONL in clinically affected pigs. C Absence of PrPSc staining in control retina. D Granular intra- and extraneuronal deposition in GCL, IPL and OPL of Sh-BSE pig.