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Table 1 Validation (qPCR) of genes involved in bile acid metabolism after S. Typhimurium infection.

From: Transcriptional analysis of porcine intestinal mucosa infected with Salmonella Typhimurium revealed a massive inflammatory response and disruption of bile acid absorption in ileum

Gene Day 2 Day 6
qPCR Array qPCR Array
APOA1 −50.00** −33.32** −1.76
C-FOS 7.00* 1.87
C-JUN 1.87 1.33
FABP2 −50.00* −48.16*** −2.58
FABP6 −200.00** −56.24* −2.28
IL-1B 30.22** 3.4* 2.92
IL-6 1.69 −1.91
NR1H4 (FXR) −3.73 −4.68* 1.34 2.02*
PPARG 1.70 1.88** 1.39
RXRG −4.09* −2.92** 1.56
SLC10A2 (ASBT) −1.92* 1.38  
STAT3 1.64   1.57 −1.6*
TLR2 2.99* 1.57* 3.43 2.41*
TLR4 10.44* 1.88* 2.25 3.52*
TLR9 −1.79   −1.29 −1.92*
TNF-α 8.68* 1.59* −1.26
  1. All values are expressed in fold change (FC) compared to controls. Asterisks indicate statistically significant values (compared to controls).
  2. P < 0.05; ** P < 0.01; *** P < 0.001.