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Figure 2 | Veterinary Research

Figure 2

From: Experimental infection of a US spike-insertion deletion porcine epidemic diarrhea virus in conventional nursing piglets and cross-protection to the original US PEDV infection

Figure 2

Antigen distribution pattern of S-INDEL PEDV Iowa106 strain (A), the original US PEDV PC21A strain (B and C), and mock (D) in jejunum. PEDV nucleocapsid proteins were detected by immunohistochemistry staining (brown) using monoclonal antibody SD6-29 against the N protein of PEDV. Both S-INDEL PEDV Iowa106 (A) and the original US PEDV PC21A (B and C) antigens were mainly detected in villous epithelial cells. Severe villous atrophy was observed in the original US PEDV PC21A-inoculated pigs (B). Incidentially, dominant villous atrophy along with the original US PEDV PC21A antigen located in crypts (arrow) were noted in one piglet (litter E, no. 3) (C).

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Veterinary Research

ISSN: 1297-9716