Figure 8

Inoculation of E75CV1 protects against the cytokine storm provoked by homologous E75 lethal challenge (Box 1 from experiment 3). Groups of four pigs were either inoculated with 10⁴ HAU₅₀ E75CV1 or non-immunized (control) and 31 days later were challenged with a lethal dose of 10⁴ HAU₅₀ E75. The delivery of cytokines and soluble cellular factors to the sera of the infected pigs was measured throughout the ASFV-challenge by specific ELISAs for: IFN-α (A), TNF-α (B) and sCD163 (C). Graphs show average values and standard deviations per group (*p < 0.05; **p < 0.01 and ***p < 0.001).