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Figure 1 | Veterinary Research

Figure 1

From: Multifunctional roles of leader protein of foot-and-mouth disease viruses in suppressing host antiviral responses

Figure 1

Structure of FMDV genome and proteolytic processing of viral polyprotein. The ORF of the viral proteins is displayed in the boxed area. The noncoding regions consist of the 5′ UTR and the 3′ UTR with a poly(A) tail. The viral functional elements in the 5′ UTR include the S fragment, the polycytidylic acid region [poly(C)], the pseudoknot structures (PKs), the cis-acting replicative element (cre), and the IRES. The 5′ end of the 5′ UTR is covalently bound to the viral 3B (or VPg) protein, which is crucial for viral RNA replication.

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Veterinary Research

ISSN: 1297-9716