Figure 6From: F4+ ETEC infection and oral immunization with F4 fimbriae elicits an IL-17-dominated immune response Cytokine secretion by F4 fimbriae stimulated naïve PBMCs. PBMCs were stimulated with endotoxin-free F4 fimbriae (5 μg/mL) or medium for 72 h. The protein level of IL-17A, IL-22, IFN-γ and IL-10 in the supernatant was determined by ELISA. Data are presented as the mean ± SEM (n = 3). NS: non-stimulated, * p < 0.05, ** p < 0.01.Back to article page