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Table 1 Variant amino acids encoded by WNV lineage 2 genome sequences of Hun2004, Aus2008 and Gr2011

From: Evaluation of the pathogenicity of West Nile virus (WNV) lineage 2 strains in a SPF chicken model of infection: NS3-249Pro mutation is neither sufficient nor necessary for conferring virulence

Genome sequence name (Genbank accession number)

Mature peptide

Amino acid position in mature peptide (Amino acid position in polyprotein)

E

NS1

NS2a

NS2b

NS3

NS4b

NS5

88 (378)

69 (860)

1 (1140)

119 (1493)

249 (1754)

14 (2287)

49 (2322)

113 (2386)

25 (2554)

Hun2004 (DQ116961)

Ser

Gly

His

Val

His

Ser

Thr

Val

Ala

Aus2008 (KF179640)

Pro

Glu

Tyr

Val

His

Ser

Thr

Val

Thr

Gr2011 (JN398476)

Pro

Glu

Tyr

Ile

Pro

Gly

Ala

Met

Thr

  1. Residues that are unique to Gr2011 when compared to Hun2004 and Aus2008 are italicized. (Adapted from [19, 46] and from a personal communication from Sylvie Lecollinet and Céline Bahuon (Anses))