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Figure 6 | Veterinary Research

Figure 6

From: Maternal and fetal predictors of fetal viral load and death in third trimester, type 2 porcine reproductive and respiratory syndrome virus infected pregnant gilts

Figure 6

Margin plots showing relative influence of statistically significant factors on PRRSV load in fetal thymus. The predicted effect on viral load in fetal thymus was calculated across a natural range of X-axis levels while the remaining factors were kept constant at their mean. Levels of IL12 (C) in supernatants of PRRSV stimulated PBMC collected at 19 dpi and absolute numbers of myeloid cells over time (AUC0-19; B) were negatively associated with viral load in fetal thymus. Fetal preservation category (F), viral load at the maternal-fetal interface (A), the number of adjacent dead fetuses (E), and the number of adjacent PRRSV RNA positive fetuses (D) were positively associated with thymic viral load. Of the six factors, PRRS RNA concentration at the maternal-fetal interface clearly demonstrated the largest effect on fetal viral load in this experiment. Error bars represent 95% confidence intervals.

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