Table 2 Age-dependent responsiveness of chickens to S. Enteritidis infection

Cytokines

IL-1β

interleukin 1

21.1 ± 14.4 ^$

2.6 ± 1.4

4.2 ± 3.8

CXCLi2 (IL-8 L2)

interleukin 8

5.9 ± 1.6

9.4 ± 4.9

7.1 ± 4.5

IL-17

interleukin 17

2.9 ± 1.5

14.4 ± 8.5

12.4 ± 10.3

IL-22

interleukin 22

50.1 ± 30.4

44.4 ± 27.9

12.3 ± 9.8

IFNγ

interferon gamma

20.1 ± 12.1

6.9 ± 3.6

2.7 ± 1.7

AH221

chemokine AH221 (CCLi9)

36.8 ± 7.4

3.6 ± 2.0

4.1 ± 2.5

IgM

immunoglobulin M heavy chain, C-region

25.8 ± 10.0

2.9 ± 1.0

1.8 ± 0.9

IgY

imunoglobulin Y heavy chain, C-region

44.9 ± 18.2

3.6 ± 1.5

0.9 ± 0.3

IgA

imunoglobulin A heavy chain, C-region

19.3 ± 11.8

2.9 ± 1.3

1.5 ± 0.4

Ig λ

immunoglobulin lambda light chain, C-region

25.1 ± 8.8

3.1 ± 1.6

0.6 ± 0.2

IRG1

immune responsive gene 1

186.2 ± 42.9

22.5 ± 11.5

25.6 ± 20.0

iNOS

inducible NO synthase

58.1 ± 18.1

5.8 ± 3.9

22.0 ± 19.7

MRP126

MRP-126 (S100A9, calprotectin, calgranulin B)

33.0 ± 13.6

10.1 ± 4.2

9.3 ± 11.3

PTGDS

prostaglandin D2 synthase 21 kDa (brain)

11.9 ± 4.0

2.2 ± 1.0

7.4 ± 5.5

C3

complement 3

11.4 ± 2.2

3.5 ± 1.1

2.5 ± 1.0

IFIT5

interferon-induced protein with tetratricopeptide repeats 5

3.6 ± 0.9

4.5 ± 2.5

8.8 ± 5.1

ASL2

argininosuccinate lyase

4.5 ± 1.0

2.6 ± 1.0

2.6 ± 1.2

MPEG1

macrophage-expressed gene 1 protein-like

4.0 ± 0.6

1.3 ± 0.2

2.6 ± 0.9

ITGB2

integrin beta-2 precursor

6.6 ± 1.1

1.6 ± 0.4

2.3 ± 1.0

TAP1

transporter 1, ATP-binding cassette, sub-family B

5.0 ± 1.4

2.4 ± 0.9

3.4 ± 1.4

STAT1

signal transducer and activator of transcription 1

4.1 ± 0.6

1.8 ± 0.4

3.0 ± 1.2

STAT3

signal transducer and activator of transcription 3

1.9 ± 0.2

1.2 ± 0.2

2.1 ± 0.6

SAA

serum amyloid A

150.7 ± 61.1

15.4 ± 9.7

22.5 ± 22.8

AVD

avidin

27.0 ± 8.4

10.1 ± 5.4

8.9 ± 5.9

HPX

hemopexin

7.0 ± 2.7

3.0 ± 2.1

3.5 ± 1.5

MMP7

matrix metallopeptidase 7 (matrilysin, uterine)

939.1 ± 287.1

138.8 ± 149.1

12.6 ± 11.4

ExFABP

extracellular fatty-acid binding protein (P20K, LCN8)

177.0 ± 57.4

27.7 ± 14.5

11.6 ± 10.1

TRAP6

trappin-6

64.8 ± 22.5

3.8 ± 2.1

10.6 ± 10.0

LYG2

lysozyme g-like 2

32.9 ± 6.3

4.5 ± 3.1

15.8 ± 8.6

MUC2L

mucin-2-like

3.5 ± 1.3

8.5 ± 4.9

2.2 ± 1.5

SERPINB10

serpin peptidase inhibitor, clade B (ovalbumin), member 10

18.0 ± 9.8

3.8 ± 1.5

8.8 ± 6.3

HCLS1

hematopoietic lineage cell-specific protein 1

7.8 ± 1.5

1.8 ± 0.6

1.9 ± 0.8

RSFR

leucocyte ribonuclease A-2, angiogenin

7.5 ± 1.7

1.7 ± 0.5

1.9 ± 0.9

Other

TGM4

glutamine γ-glutamyltransferase 4

37.5 ± 12.0

2.3 ± 1.1

9.9 ± 13.9

ES1

ES1 protein homolog

21.4 ± 8.9

22.4 ± 17.8

17.5 ± 13.0

EPSTI1

epithelial stromal interaction 1 (breast)

3.6 ± 0.9

3.1 ± 0.9

1.7 ± 0.8