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Table 2 Viral load of organs in Ct values, copies per mg organ and tissue culture infectious dose 50 (TCID50) per mg organ

From: DNA vaccines encoding the envelope protein of West Nile virus lineages 1 or 2 administered intramuscularly, via electroporation and with recombinant virus protein induce partial protection in large falcons (Falco spp.)

Falcons Brain Spleen Kidney Lung Liver Heart
Grp ID Dpi Ct Copies TCID Ct Copies TCID Ct Copies TCID Ct Copies TCID Ct Copies TCID Ct Copies TCID
A F25 20 30.5 40.6 0.5 N 0 0 N 0 0 N 0 0 N 0 0 N 0 0
F26 8 17.4 360248.4 48899.3 18.4 287861 432 22.1 28394.8 558.7 29.1 384.8 1814 19.8 43699.3 312.8 21.1 43844.8 139.7
F28 21 31.1 84.6 0 N 0 0 31 155.6 0 N 0 0 N 0 0 N 0 0
F29 4 32.9 12.2 0.6 25.2 3941.3 26.8 26.5 1081.2 1.9 28.3 511.6 5.3 27.9 448.2 0.7 30.6 69 0
F30 19 29.1 313.2 1 N 0 0 33.1 19.2 0 N 0 0 N 0 0 N 0 0
B F31 21 33.1 3.3* 0 N 0* 0 N 0* 0 N 0 0 N 0 0 N 0* 0
F32 19 33.1 2.6* 0 N 0* 0 32.6 6.2* 0 N 0 0 N 0 0 N 0* 0
F33 21 N 0* 0 N 0* 0 N 0* 0 N 0 0 N 0 0 N 0* 0
F34 20 29.4 38* 0 N 0* 0 N 0* 0 N 0 0 N 0 0 N 0* 0
F35 19 N 0* 0 N 0* 0 N 0* 0 N 0 0 N 0 0 N 0* 0
C F49 20 32.3 26.5 0 N 0* 0 N 0* 0 N 0 0 N 0 0 N 0* 0
F50 20 31.4 36.3 0 N 0* 0 N 0* 0 N 0 0 N 0 0 N 0* 0
F52 19 N 0 0 N 0* 0 N 0* 0 N 0 0 N 0 0 N 0* 0
F53 19 N 0 0 N 0* 0 N 0* 0 N 0 0 N 0 0 N 0* 0
F54 21 30.4 23.3 0 N 0* 0 N 0* 0 N 0 0 N 0 0 N 0* 0
D F56 19 30.5 35.3 0 N 0 0 N 0* 0 N 0 0 N 0 0 N 0 0
F57 21 26.7 192.7 0 N 0 0 32.3 6.6* 0 N 0 0 N 0 0 N 0 0
F58 21 31.6 14 0 N 0 0 N 0* 0 N 0 0 N 0 0 N 0 0
F59 18 19.9 40297.1 62.2 30.6 44.7 0 34.3 1.9 0 33.7 1.9 0 33.8 4.3 0 31.8 14 0
F60 20 30.4 39.6 0 36.4 2.6 0 35.5 1.4* 0 N 0 0 N 0 0 N 0 0
E F13 19 28.3 111.6 0.6 30.8 17.9 0 32.7 3.9 0 39.7 0.1 0 36.3 0.3 0 N 0 0
F24 20 31.6 32.1 0 N 0 0 36.1 821.8 0 N 0 0 N 0 0 39.3 4.7 0
F27 14 21.3 132202.1 8.7 31.8 42 0 28.9 403.3 0 33.1 36.9 0 34.2 16.7 0 24.4 7793.8 37.9
F36 20 31 23.6 0 N 0 0 34.9 2 0 N 0 0 N 0 0 N 0 0
F42 5 27.3 514.8 47 20.7 318323 174.6 23.2 14400 76.2 25 5456.3 600.8 23.2 32118.9 94.4 24.8 6562.9 19
F43 20 30.9 38.2 0.4 33.7 11.4 0 36.5 1.5 0 N 0 0 41.4 0.1 0 41.5 0.1 0
F51 8 22.7 2667.5 737.9 22.5 8631 10.6 18.9 82090.5 2895.9 19.8 63844.1 7558.4 16.7 402895.4 3023.2 17.7 295310.6 4379.9
F55 3 31 12.3 0 23.9 2375.9 3.4 25.7 795.6 3.9 26.4 464.9 13.2 26.7 248.5 0.9 27.7 379.8 5.4
  1. Abbreviations: Grp (group), ID (identification number), Dpi (days post infection), Ct (Ct values), Copies (copies per mg organ), TCID (tissue culture infectious dose 50 per mg organ), N (no Ct value). Viral genome copies of brain, spleen, kidney and heart of all surviving birds of the vaccination groups were compared to the respective values of group E with one-sided Wilcoxon rank sum test with continuity correction and those with statistical significant difference were indicated with an asterisk (p-values < α-levels of 0.05 were classified as significant).
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Veterinary Research

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