CyPA is secreted in cattle during inflammation. Immunohistochemical analysis shows that extracellular CyPA is abundantly found in alveoli and ducts of bovine mammary gland with mastitis (shown by arrowheads). A-C and E-G (both of which were stained with anti-CyPA antibody) are images showing individual healthy cattle and individual cattle with mastitis, respectively. D (healthy) and H (mastitis) are images stained with control antibody. Scale bar = 100 μm.