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Figure 1 | Veterinary Research

Figure 1

From: Acquired transmissibility of sheep-passaged L-type bovine spongiform encephalopathy prion to wild-type mice

Figure 1

Immunolabeled PrP Sc accumulation in the brain and lymph node of ICR mice infected with sheep-passaged L-BSE, at first passage. PrPSc accumulated in the brain of the medial preoptic nucleus (A), habenular nucleus (B), and midbrain tegmentum (C), and in the follicular dendritic cells within the secondary follicle of renal lymph node (D) of a mouse killed at 710 days post-inoculation. Immunohistochemical labeling with mAb SAF84 and hematoxylin counterstain. Scale bar = 25 μm.

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