cow ID | B0, CFU/g |
r, 10−2/day |
k
C, 10−7/day |
k
H, 10−3/day |
|---|
C01 | 6.3 | −0.2 | 0 | 0 |
C02 | 4.7 | 0.8 | −2.55 | −571.49 |
C03 | 3.6 | −0.4 | 0 | −76.32 |
C04 | 4.2 | 0.1 | 2.17 | −189.83 |
C05 | 9.2 | −0.3 | 0 | 0 |
C06 | 5 | −0.1 | 0 | 0 |
C07 | 3.9 | 0.6 | 0 | 0 |
C08 | 1 | 1.2 | 1.69 | 0 |
C09 | 2.2 | 0.6 | 0.64 | 0 |
C10 | 4.2 | 0 | 0 | −76.71 |
C11 | 8.3 | 0 | −6.9 | 76.24 |
C12 | 4.1 | −0.2 | 0 | −11.27 |
C13 | 4.2 | −0.2 | 0 | −16.06 |
C14 | 8.7 | −1.3 | −0.99 | 0 |
C15 | 9.7 | 0.4 | 1.03 | 0 |
C16 | 6.6 | 0.1 | 0 | −9.15 |
C17 | 0.6 | 0 | 4.69 | −165.86 |
C18 | 6.7 | −0.1 | 0 | 0 |
C19 | 9.1 | −0.9 | −0.63 | 0 |
C20 | 6.4 | −0.4 | 0 | −64.95 |
- The best fit model (the model is shown in Equation 4) was determined by performing F-tests for nested models and using Akaike weights for non-nested models (see Materials and methods for more detail and Additional file 4). Listed parameters are: B
0 is the predicted initial shedding level, r is the rate of exponential change in shedding in the absence of MAP-specific cellular (as measured by LPT) and humoral (as measured by ELISA) immune responses, k
C is the predicted rate of reduction in shedding by the cellular immune response, k
H is the predicted rate of reduction in shedding by the humoral immune response. Negative values in shedding rate change r indicate predicted decline in shedding in the absence of measurable cellular and antibody responses. Negative values in k
C and k
H indicate increase in shedding with the presence of corresponding immune responses.
