|
cow ID
|
B0, CFU/g
|
r, 10−2/day
|
k
C, 10−7/day
|
k
H, 10−3/day
|
|---|
|
C01
|
6.3
|
−0.2
|
0
|
0
|
|
C02
|
4.7
|
0.8
|
−2.55
|
−571.49
|
|
C03
|
3.6
|
−0.4
|
0
|
−76.32
|
|
C04
|
4.2
|
0.1
|
2.17
|
−189.83
|
|
C05
|
9.2
|
−0.3
|
0
|
0
|
|
C06
|
5
|
−0.1
|
0
|
0
|
|
C07
|
3.9
|
0.6
|
0
|
0
|
|
C08
|
1
|
1.2
|
1.69
|
0
|
|
C09
|
2.2
|
0.6
|
0.64
|
0
|
|
C10
|
4.2
|
0
|
0
|
−76.71
|
|
C11
|
8.3
|
0
|
−6.9
|
76.24
|
|
C12
|
4.1
|
−0.2
|
0
|
−11.27
|
|
C13
|
4.2
|
−0.2
|
0
|
−16.06
|
|
C14
|
8.7
|
−1.3
|
−0.99
|
0
|
|
C15
|
9.7
|
0.4
|
1.03
|
0
|
|
C16
|
6.6
|
0.1
|
0
|
−9.15
|
|
C17
|
0.6
|
0
|
4.69
|
−165.86
|
|
C18
|
6.7
|
−0.1
|
0
|
0
|
|
C19
|
9.1
|
−0.9
|
−0.63
|
0
|
|
C20
|
6.4
|
−0.4
|
0
|
−64.95
|
- The best fit model (the model is shown in Equation 4) was determined by performing F-tests for nested models and using Akaike weights for non-nested models (see Materials and methods for more detail and Additional file 4). Listed parameters are: B
0 is the predicted initial shedding level, r is the rate of exponential change in shedding in the absence of MAP-specific cellular (as measured by LPT) and humoral (as measured by ELISA) immune responses, k
C is the predicted rate of reduction in shedding by the cellular immune response, k
H is the predicted rate of reduction in shedding by the humoral immune response. Negative values in shedding rate change r indicate predicted decline in shedding in the absence of measurable cellular and antibody responses. Negative values in k
C and k
H indicate increase in shedding with the presence of corresponding immune responses.
