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Table 1 Parameters and dependent variables and their interpretation

From: An immuno-epidemiological model for Johne’s disease in cattle

Variable or parameter

Meaning

M u (τ)

Number of uninfected macrophages at time τ

M i (τ)

Number of infected macrophages at time τ

C (τ)

Number of immune cells at time τ

r

Total recruitment rate for uninfected cells

α

Infection rate of uninfected macrophages by infected macrophages

d 1

Natural death rate for uninfected macrophages

δ

Death rate of infected macrophages

d 2

Clearance rate for immune cells

k

Stimulation rate of immune response from infected cells

ε 1

Reciprocal of half saturation constant for killing of infected macrophages

ε 2

Reciprocal of half saturation constant for immune response stimulation rate

ε 3

Reciprocal of half saturation constant for killing of infected macrophages

c

Reciprocal of half saturation constant for macrophages infection rate

p

Killing rate of infected macrophages by immune response.