Figure 1From: Incubation of ovine scrapie with environmental matrix results in biological and biochemical changes of PrPSc over time Incubation periods of mice after challenge with scrapie. Mice were inoculated with extracts of soil incubated with a pool of classical scrapie isolates or with a dilution series of the same scrapie pool without soil incubation g/mL of brain inoculum are shown). Open circles: the PrPSc distribution phenotype G338; open triangles: Apl338ii; square: Cag338; solid triangles: G338/Apl338ii mix; diamond: P338/Apl338ii mix. Each vertical line indicates the mean incubation period of a group of mice irrespective of their PrPSc distribution phenotype. 1D and 13Â M are the prion eluted from soil after a 1Â day or 13Â month incubation respectively.Back to article page