Skip to main content

Table 4 Down-regulated canonical pathways in PMEC at 3 hpc

From: Gene expression profiling of porcine mammary epithelial cells after challenge with Escherichia coli and Staphylococcus aureus in vitro

E. coli- challenged vs. unchallenged control cells

 

Canonical pathway (Genes involved in pathway)

p -value

BMP signaling pathway(SOSTDC1,JUN,BMP4,BMP2)

1.27E-04

Regulation of IL-2 Expression in Activated and AnergicT Lymphocytes(FOS,JUN,NFKBIA,VAV3)

1.55E-04

TGF-b Signaling(FOS,JUN,BMP4,BMP2)

1.79E-04

T Cell Receptor Signaling(FOS,JUN,NFKBIA,VAV3)

2.84E-04

PKCq Signaling in T Lymphocytes(FOS,JUN,NFKBIA,VAV3,MAP3K8)

4.80E-04

S. aureus- challenged vs. unchallenged control cells

 

Canonical pathway (Genes involved in pathway)

p -value

Differential Regulation of Cytokine Production inMacrophages and T Helper Cells by IL-17A and IL-17 F(CXCL1,CSF2)

1.75E-04

Role of Tissue Factor in Cancer(EGR1,CXCL1,JAK2,CSF2)

2.35E-04

Differential Regulation of Cytokine Production inIntestinal Epithelial Cells by IL-17A and IL-17 F (CXCL1,CSF2)

2.88E-04

IL-17A Signaling in Gastric Cells(FOS,CXCL1)

3.42E-04

MIF Regulation of Innate Immunity(FOS,PTGS2)

9.24E-04

  1. Top five categories of down-regulated canonical pathways in PMEC at 3 hpc with E. coli and S. aureus, respectively, compared with unchallenged control cells with their respective p-value and genes involved in each pathway obtained from IPA software.
Back to article page

Veterinary Research

ISSN: 1297-9716