Skip to main content

Table 1 Molecular and cellular functions affected in PMEC by pathogen challenge

From: Gene expression profiling of porcine mammary epithelial cells after challenge with Escherichia coli and Staphylococcus aureus in vitro

3 h E. coli- challenged vs. unchallenged control cells p -value #Molecules
Gene Expression 1.72E-14 - 1.71E-04 46
Cellular Growth and Proliferation 3.56E-14 - 3.13E-04 55
Cellular Development 1.46E-13 - 3.95E-04 52
Cell Death and Survival 1.29E-11 - 3.95E-04 50
Cellular movement 4.13E-11 - 3.95E-04 40
3 hS. aureus- challenged vs. unchallenged control cells p -value #Molecules
Small Molecule Biochemistry 4.30E-08 - 4.53E-03 14
Drug Metabolism 2.15E-07 - 4.53E-03 8
Lipid Metabolism 2.15E-07 - 4.53E-03 11
Vitamin and Mineral Metabolism 2.15E-07 - 3.39E-03 4
Energy Production 8.97E-07 - 2.27E-03 4
24 h E. coli- challenged vs. unchallenged control cells p -value #Molecules
Cellular Growth and Proliferation 1.46E-15 - 5.35E-03 255
RNA Post-Transcriptional Modification 3.21E-14 - 4.88E-03 53
Cell Cycle 1.46E-12 - 4.88E-03 115
Cell Death and Survival 7.44E-10 - 5.09E-03 226
Cellular Development 4.90E-08 - 5.35E-03 219
24 hS. aureus- challenged vs. unchallenged control cells p -value #Molecules
RNA Post-Transcriptional Modification 9.24E-15 - 1.62E-02 42
Cell Cycle 8.61E-10 - 1.62E-02 95
Cellular Growth and Proliferation 8.88E-10 - 1.37E-02 202
Cell Death and Survival 4.29E-08 - 1.62E-02 187
Gene Expression 3.25E-07 - 6.69E-03 156
  1. Top five categories of molecular and cellular functions affected in PMEC at 3 h and at 24 h post-challenge with E. coli and S. aureus, respectively, compared with unchallenged control cells with their respective p-value and number of molecules included in each class obtained from IPA software.