Table 1 Molecular and cellular functions affected in PMEC by pathogen challenge
3 h E. coli- challenged vs. unchallenged control cells | p -value | #Molecules |
|---|---|---|
Gene Expression | 1.72E-14 - 1.71E-04 | 46 |
Cellular Growth and Proliferation | 3.56E-14 - 3.13E-04 | 55 |
Cellular Development | 1.46E-13 - 3.95E-04 | 52 |
Cell Death and Survival | 1.29E-11 - 3.95E-04 | 50 |
Cellular movement | 4.13E-11 - 3.95E-04 | 40 |
3 h S. aureus- challenged vs. unchallenged control cells | p -value | #Molecules |
Small Molecule Biochemistry | 4.30E-08 - 4.53E-03 | 14 |
Drug Metabolism | 2.15E-07 - 4.53E-03 | 8 |
Lipid Metabolism | 2.15E-07 - 4.53E-03 | 11 |
Vitamin and Mineral Metabolism | 2.15E-07 - 3.39E-03 | 4 |
Energy Production | 8.97E-07 - 2.27E-03 | 4 |
24 h E. coli- challenged vs. unchallenged control cells | p -value | #Molecules |
Cellular Growth and Proliferation | 1.46E-15 - 5.35E-03 | 255 |
RNA Post-Transcriptional Modification | 3.21E-14 - 4.88E-03 | 53 |
Cell Cycle | 1.46E-12 - 4.88E-03 | 115 |
Cell Death and Survival | 7.44E-10 - 5.09E-03 | 226 |
Cellular Development | 4.90E-08 - 5.35E-03 | 219 |
24 h S. aureus- challenged vs. unchallenged control cells | p -value | #Molecules |
RNA Post-Transcriptional Modification | 9.24E-15 - 1.62E-02 | 42 |
Cell Cycle | 8.61E-10 - 1.62E-02 | 95 |
Cellular Growth and Proliferation | 8.88E-10 - 1.37E-02 | 202 |
Cell Death and Survival | 4.29E-08 - 1.62E-02 | 187 |
Gene Expression | 3.25E-07 - 6.69E-03 | 156 |