Comparative analysis of cytokine transcript profiles within mediastinal lymph node compartments of pigs after infection with porcine reproductive and respiratory syndrome genotype 1 strains differing in pathogenicity

Table 2 Correlations between LV RNA and the gene expression of TNF-α, IFN-α, IFN-γ, SOCS1, IL-23p19, IL-10 and TGF-β

		IFN-α	IFN-γ	IL-23	SOCS1	IL-10	TGF-β	ORF7 PRRSV
TNF-α	F	0.857**	0.094	−0.102	0.064	0.160	0.964**	−0.077
	IF	0.184	0.469	0.643*	0.471	0.687**	0.479	−0.190
	T	0.750**	0.248	0.031	0.091	0.305	0.921**	−0.043
IFN-α	F		−0.255	−0.351	0.009	−0.201	0.901**	−0.110
	IF		0.307	0.276	−0.086	0.094	0.619*	−0.663**
	T		−0.142	−0.156	−0.132	0.167	0.880**	−0.301
IFN-γ	F			0.342	0.607*	0.131	−0.082	0.413
	IF			0.220	0.680**	0.100	0.282	0.144
	T			0.167	0.649**	0.222	0.008	0.438
IL-23	F				0.239	0.112	−0.179	−0.208
	IF				0.109	0.553*	0.183	−0.231
	T				−0.004	0.395	−0.106	−0.154
SOCS1	F					0.809	−0.063	0.527*
	IF					0.310	−0.016	0.303
	T					0.211	−0.139	0.486
IL-10	F						−0308	0.397
	IF						0.116	−0.332
	T						0.144	−0.151
TGF-β	F							−0.206
	IF							−0.557*
	T							−0.245

*p < 0.05; **p < 0.01. F (follicle of Med-LN), IF (interfollicular area of Med-LN) and T (Total cortical compartments of Med-LN).

ISSN: 1297-9716