Gene | Function | Reference |
---|---|---|
CSNK2A1 | Plays key role in cellular growth and differentation. Suppressor of Apoptosis | [33] |
EP400 | Promotes cell cycle progression and inhibits induction of apoptosis or senescence. | [34] |
NUB1 | Role in cell cycle progression. | [35] |
MKI67IP | Interacts with Ki-67 in proliferating cells and has a role in mitosis | [36] |
TPD52L2 | Regulator of cell proliferation. Marker for breast cancer and acute lymphoblastic leukemia. | [37] |
RPS8 | Role in apoptosis. Reacts with CDK11p46 and sensitizes cells for Fas ligand-induced apoptosis | [38] |
PPP1CA | Regulates cell cycle progression and apoptosis. | [39] |
BAG6 | Represses function of Tim3 expressed on T cells during Hepatitis C virus infection. Regulates Apoptosis. | [40] |
PPP5C | Regulates signaling cascades that suppress growth or induces apoptosis. | [41] |
IFIT3 | Induces antiviral response (anti-viral signaling) by inducing IFN-alpha. | [42] |
CD3D | Involved in T cell development. Mutation in this gene leads to Immunodeficiency (SCID) | [43] |
APP | Signaling molecule Involved in synaptic adhesion. Processed to form ß-amyloid peptides | [44] |
VCP | Chaperon protein that regulates DNA damage and repair | [45] |