Group
|
Foetal death (dpi)
|
Placenta
|
Liver
|
Brain
|
---|
| |
Histology
α
|
PCR
β
|
Histology
α
|
PCR
β
|
Histology
α
|
PCR
β
|
---|
| |
No. foci/cm
2
|
ASF (mm
2
)
|
%LES
|
No. foci/cm
2
|
ASF (mm
2
)
|
%LES
|
No. foci/cm
2
|
ASF (mm
2
)
|
%LES
|
---|
G1 (day 40) | 19-21 | 8.2d
| 0.053d
| 0.25%d
| 6/6 (7888c) | 82.3c
| 0.041 | 3.37%c
| 11/11a (6318c) | 1.68 | 0.038 | 0.05% | 11/11 (1697c) |
G2 (day 90) | 34-48 | 73.0c
| 0.113d
| 9.07%c
| 7/7 (308.5d) | 0.2d
| 0.044 | 0.02%d
| 5/12b (0.01d) | 3.14 | 0.047 | 0.18% | 10/12 (0.25d) |
G3 (day 120) | Born* | 18.7d
| 0.304c
| 5.74%c
| 7/7 (190.8d) | 4.2d
| 0.047 | 0.16%d
| 4/9b (0.01d) | 3.50 | 0.063 | 0.25% | 6/9 (0.01d) |
- *All lambs from this group gave birth to viable lambs between days 142 and 155 of gestation.
-
αAverage values of histological scoring for each group.
-
βFractions represent the number of positive animals/total number of animals checked by nested-ITS1 PCR, and figures within brackets represent the median values of parasite burden (tachyzoites/mg tissue).
-
a,bFractions determined for positive animals followed by unlike superscripts differ significantly by Fisher’s exact test.
-
c,dValues followed by unlike superscripts differ significantly by Dunn’s test for pairwise comparisons.
- dpi: days post infection when abortion occurred; ASF: Average size of focus; %LES: Percentage of section affected by lesions.