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Table 4 Flavivirus specific antibody levels in foals born to vaccinated mares and vaccinated at 36–83 days of age, followed by booster vaccinations four weeks and approximately one year later

From: Safety and immunogenicity of a delta inulin-adjuvanted inactivated Japanese encephalitis virus vaccine in pregnant mares and foals

Time point JEV neutralizing MVEV neutralizing WNVKUNneutralizing
  Positive/total Mean titre≠ Titre range Positive/total Mean titre≠ Titre range Positive/total Mean titre≠ Titre range
Pre-suckle 0/11 -- -- 0/11 -- -- 0/11 -- --
Post suckle 10/11 46 < 20-80 8/11 30 < 20-40 3/11 93 < 20-160
Age 13–49 days 3/10* 26 < 20-40 1/10* 40 < 20-40 2/10* 30 < 20-40
Vaccination 3/11 20 < 20-20 2/11 20 < 20-20 1/11 40 < 20-40
Age 36–83 days
Booster 4 weeks post vaccination 2/11 20 < 20-20 3/11 20 < 20-20 2/11 20 < 20-20
Age 64–111 days
4 weeks post booster 10/11 88 < 20-320 10/11 30 < 20-40 1/11 20 < 20-20
Age 93–140 days
7 weeks post booster 3/11 53 < 20-80 6/11 26 < 20-40 3/11 20 < 20-20
Age 114–161 days
10 weeks post booster 5/11 24 < 20-40 0/11 - < 20 1/11 20 < 20-20
Age 137–184 days
~9 months post 1 st boost (2 nd boost) 0/11 -- < 20 0/11 -- < 20 0/11 -- < 20
Age 332–379 days
2 weeks post 2 nd boost 11/11 > 902 160- > 2560 10/11 50 < 20-80 1/11 20 < 20-20
Age 346–393 days
5.5 weeks post 2 nd boost 11/11 465 160-1280 7/11 17 < 20-40 0/11 - < 20
Age 370–417 days
14 weeks post 2 nd boost 8/11 150 < 20-640 0/11 - < 20 9/11 31 < 20-80
Age 454-501
20 weeks post 2 nd boost 7/11 63 < 20-160 0/11 - < 20 0/11 - < 20
Age 498–545 days
  1. *one foal not yet born at this sampling point.
  2. ≠mean of titres ≥ 20.
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Veterinary Research

ISSN: 1297-9716