Bovine Neonatal Pancytopenia is a heritable trait of the dam rather than the calf and correlates with the magnitude of vaccine induced maternal alloantibodies not the MHC haplotype

Table 4 Comparison of DRB3 allele frequencies within Pregsure© BVD vaccinated dams and BNP dams

DRB3 allele frequencies	Non-BNP dams (n = 21)	BNP dams (n = 21)	P-value^a	FDR-derived significance thresholds^b
1001	7	1	0.0574	0.004
14011	7	1	0.0574	0.008
2703	2	7	0.1555	0.013
0902	2	6	0.2646	0.017
1601	1	4	0.3597	0.021
0201	4	1	0.3597	0.025
0101	3	6	0.4827	0.029
0601	2	0	0.494	0.033
1101	9	11	0.7983	0.038
1201	3	4	1.000	0.042
0701	1	0	1.000	0.046
UU01^c	1	1	1.000	0.050

^aOrdered P-values from Fisher’s exact test.
^bTo adjust for multiple comparisons the False Discovery Rate (FDR) was controlled at 5% using the principle from Benjamini and Hochberg [19]. The largest P-value lower than its FDR-derived significance threshold and all P-values smaller are significant.
^cDenotes a local name and is not included in the IPD Bovine MHC class II database.

ISSN: 1297-9716