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Table 4 Comparison of DRB3 allele frequencies within Pregsure© BVD vaccinated dams and BNP dams

From: Bovine Neonatal Pancytopenia is a heritable trait of the dam rather than the calf and correlates with the magnitude of vaccine induced maternal alloantibodies not the MHC haplotype

DRB3 allele frequencies Non-BNP dams (n  = 21) BNP dams (n  = 21) P-valuea FDR-derived significance thresholdsb
1001 7 1 0.0574 0.004
14011 7 1 0.0574 0.008
2703 2 7 0.1555 0.013
0902 2 6 0.2646 0.017
1601 1 4 0.3597 0.021
0201 4 1 0.3597 0.025
0101 3 6 0.4827 0.029
0601 2 0 0.494 0.033
1101 9 11 0.7983 0.038
1201 3 4 1.000 0.042
0701 1 0 1.000 0.046
UU01c 1 1 1.000 0.050
  1. aOrdered P-values from Fisher’s exact test.
  2. bTo adjust for multiple comparisons the False Discovery Rate (FDR) was controlled at 5% using the principle from Benjamini and Hochberg [19]. The largest P-value lower than its FDR-derived significance threshold and all P-values smaller are significant.
  3. cDenotes a local name and is not included in the IPD Bovine MHC class II database.