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Table 2 Comparison of MHC class I haplotype frequencies in Pregsure© BVD vaccinated non-BNP and BNP dams

From: Bovine Neonatal Pancytopenia is a heritable trait of the dam rather than the calf and correlates with the magnitude of vaccine induced maternal alloantibodies not the MHC haplotype

MHC class I Haplotypea Non-BNP dams (n  = 27) BNP dams (n  = 22) P-valueb FDR-derived significance thresholdsc
A19 variants 5 11 0.053 0.003
H2 4 0 0.125 0.006
A13 2 6 0.135 0.009
UU6 0 2 0.199 0.012
UU5 0 1 0.449 0.015
A20v3 (UU) 5 2 0.454 0.018
UU1 2 0 0.500 0.021
A11 3 1 0.625 0.024
A10 4 2 0.688 0.026
H5v2 (UU) 4 2 0.688 0.029
A14 9 6 0.782 0.032
A15v1 9 8 1.000 0.035
A12vUU 3 2 1.000 0.038
UU3 1 0 1.000 0.041
A18v2 1 0 1.000 0.044
UU4 1 0 1.000 0.047
UU7 1 1 1.000 0.050
  1. aBovine MHC class I haplotypes are based on Codner et al. [17] and results from this study (detailed in Additional file 2).
  2. bOrdered P-values from Fisher’s exact test.
  3. cTo adjust for multiple comparisons the False Discovery Rate (FDR) was controlled at 5% using the principle from Benjamini and Hochberg [19]. The largest P-value lower than its FDR-derived significance threshold and all P-values smaller are significant.