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Table 3 Differential expression of key immune related genes between HPAIV infected chicken and duck cells (detected by microarray)

From: Highly pathogenic avian influenza virus infection in chickens but not ducks is associated with elevated host immune and pro-inflammatory responses

Gene symbol Gene name Entrez Gene ID Chicken cells Duck cells
H5N1-tyEng91 H5N1-tyTR05 H5N1-tyEng91 H5N1-tyTR05
    Fold change Regulation Fold change Regulation Fold change Regulation Fold change Regulation
JAK-STAT Pathway          
STAT3 signal transducer and activator of transcription 3 420027 2.33 down 2.72 down 1.39 up - unchanged
JAK1 Janus kinase 1 (a protein tyrosine kinase) 554219 2.79 down 3.21 down - Removed* - Removed*
IFNAR1 Interferon (alpha, beta and omega) receptor 1 395665 8.02 down 16.65 down 13.91 up 1.37 up
PIAS2 Protein inhibitor of activated STAT, 2 416383 5.05 down 3.86 down 1.62 up 3.7 down
Cytokines and Chemokines
IL8/ CXCLi1(K60) interleukin 8 395872 232.8 up 2.96 up - unchanged - unchanged
IL6 interleukin 6 (interferon, beta 2) 395337 131.08 up 10.66 up 2.92 down - unchanged
IL10 interleukin 10 428264 1.39 up 1.6 up 1.39 down - unchanged
IL18 interleukin 18 (interferon-gamma-inducing factor) 395312 4.7 down 4.14 down 3.02 up 2.4 up
  1. *Transcript removed during probe masking.