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Figure 8 | Veterinary Research

Figure 8

From: Immunity, safety and protection of an Adenovirus 5 prime - Modified Vaccinia virus Ankara boost subunit vaccine against Mycobacterium avium subspecies paratuberculosis infection in calves

Figure 8

FoxP3 expression by T cell sub-populations from HAV- and Sham-vaccinated animals. PBMC from HAV-vaccinated (diamond) or Sham-vaccinated (square) calves were stimulated for 24 h with PPD-J or left unstimulated (control), then washed, fixed, permeablised and assessed for expression of A. CD4, B. WC1 and C. CD8. Cells were gated as live PBMC and the percentage of each cell population (CD4, CD8, WC1) expressing FoxP3 was calculated. Samples taken include week 0, immediately prior to MAP challenge and then up to 36 weeks post challenge. Significance between groups is indicated as * P < 0.05, ** P < 0.01, *** P < 0.001.

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