Identity → | tk/Ire/83 H5N8 | ck/Ind/03 H5N1 | ck/Ita/98 H5N9 | Vtn/04 H5N1 | tk/Tur/05 H5N1 | ck/WJ/07 H5N1 |
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Similarity ↓ |
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tk/Ire/83 H5N8
| | 88.0% | 91.4% | 88.7% | 88.7% | 83.4% |
ck/Ind/03 H5N1
| 94.8% | | 89.3% | 96.6% | 96.0% | 92.9% |
ck/Ita/98 H5N9
| 96.3% | 94.5% | | 89.6% | 89.3% | 85.3% |
Vtn/04 H5N1
| 95.1% | 97.5% | 93.9% | | 94.8% | 92.0% |
tk/Tur/05 H5N1
| 94.2% | 98.2% | 93.9% | 97.6% | | 90.5% |
ck/WJ/07 H5N1
| 91.1% | 94.8% | 91.7% | 94.2% | 94.2% | |
- The HA gene of A/turkey/Ireland/1378/83 [H5N8] (tk/Ire/83 H5N8) and of A/chicken/Indonesia/7/2003 [H5N1 clade 2.1.1] (ck/Ind/03 H5N1) is inserted into the genome of fowlpox recombinant vFP89 and vFP2211, respectively. The A/chicken/Italy/22A/98 [H5N9] (ck/Ita/98 H5N9) is used in the inactivated inH5N9 vaccine. The NIBRG14 and NIBRG23 reverse genetics constructs contain the HA and NA genes from A/Vietnam/1194/2004 [H5N1 clade 1] (Vtn/04 H5N1) and from A/turkey/Turkey/1/2005 [H5N1 clade 2.2] (tk/Tur/05 H5N1), respectively. The A/chicken/West Java-Subang/29/2007 [H5N1 clade 2.1.3.2] (ck/WJ/07 H5N1) was used for the challenge in study 4.