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Table 2 Presence (+) or absence (-) of virulence-associated genes in RF122 and Newbould 305

From: Fine-tuned characterization of Staphylococcus aureus Newbould 305, a strain associated with mild and chronic mastitis in bovines

Gene name
Biofilm formation Function NB305 RF122
ica operon Biofilm synthesis ica operon + +
bap Biofilm associated protein - -
aap Accumulation-associated protein (associated to biofilm formation) +* -
ypfP, ltaA, ltaS, tag and dlt operons Teichoic and Lipoteichoic acid synthesis + +
cap operon Capsular polysaccharide biosynthesis + +
Secreted toxins Function NB305 RF122
lukE Leukocidin LukE precursor + +
lukD Leukocidin LukD precursor + +
lukM Leukocidin chain lukM precursor - +
lukF’-PV Panton-Valentine leukocidin LukF’-PV chain - +
lukF Leukocidin F subunit + +
lukS leukocidin/hemolysin toxin subunit S + +
hla Alpha-hemolysin precursor + +
hlb Beta-hemolysin precursor + +
hlg (subunits A, B, C) Gamma-hemolysin component + +
hld Delta-hemolysin + -
atl Bifunctional autolysin precursor + +
tst Toxic shock syndrome toxin 1 - +
eta Exfoliative A + +
etb Exfoliative B - +
sea Staphylococcal enterotoxin A + +
sec bov Bovine variant of Staphylococcal enterotoxin C - +
seg Staphylococcal enterotoxin G - +
sei Staphylococcal enterotoxin I - +
sel Staphylococcal enterotoxin L - +
sen Staphylococcal enterotoxin N - +
seo Staphylococcal enterotoxin O - +
Colonisation factors Function NB305 RF122
vwb Secreted von Willebrand factor-binding protein (Wbp) precursor + +
vwb Sbo5 SaPI-encoded variant of Wbp carried by SaPIbov5 + -
clfA Clumping factor A + +
clfB Clumping factor B + +
fnbA Fibronectin binding protein A + +
fnbB Fibronectin binding protein B + -
stl Transcriptional Repressor SaPI + +
eap Extracellular adherence protein + +
sasG S. aureus surface protein G + -
plsC 1-acyl-sn-glycerol-3-phosphate acyltransferase + -
sak Staphylokinase - -
spa Immunoglobulin G binding protein A precursor + +
  1. *Newbould 305_2513 possess a CWA domain and is 67% similar to aap gene of S. epidermidis (GeneBank accession number YP_189945).