Figure 2

Relation between histopathological score and quantification of viral antigen in pH1N1-infected ferrets. (A) Linear regression shows the correlation between IAV antigen quantification and histopathological scores at 4 dpi, independently of viral strains (*p value < 0.05). (B) Relation between viral load measured by RT-PCR and histopathological score; GEC of plasmid per gram of lung tissue. (C) Immunohistochemical cell quantification of IAV-positive cells in ferret lungs segregated by histopathological score; Results express the mean cell counts with SEM (20× objective field).