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Table 3 Histological lesions (HE) and presence of antigen (IHC) in tissues of H5N1-inoculated gulls during the course of the experiment

From: Experimental infection of highly pathogenic avian influenza virus H5N1 in black-headed gulls (Chroicocephalus ridibundus)

 

Number of birds positive/number of birds examined per day

 

2 dpi

4 dpi

5 dpi

6 dpi

7 dpi

12 dpi

Tissue

HE1

IHC2

HE

IHC

HE

IHC

HE

IHC

HE

IHC

HE

IHC

Thymus

0/4

2/4

0/5

0/5

0/2

0/2

0/2

0/2

0/1

0/1

0/2

0/2

Adrenal

1/4

1/4

0/5

0/5

0/2

0/2

1/2

1/2

0/1

0/1

0/2

0/2

Lung/Trachea

0/4

3/4

1/5

0/5

1/2

0/2

1/2

0/2

0/1

0/1

0/2

0/2

Air sacs

4/4

4/4

5/5

5/5

2/2

1/2

1/2

1/2

0/1

0/1

1/2

1/2

Pancreas

0/4

0/4

2/5

2/5

1/2

1/2

2/2

2/2

1/1

1/1

1/2

0/2

CNS

0/4

0/4

5/5

5/5

2/2

2/2

2/2

2/2

1/1

1/1

1/2

0/2

  1. 1HE: presence of histological lesions by examination of hematoxylin-and-eosin-stained tissue sections.
  2. 2IHC: presence of viral antigen by examination of tissue sections stained by immunohistochemical technique.