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Table 1 Serological results

From: Single immunization with an inactivated vaccine protects sheep from Schmallenberg virus infection

Animal

Group

SNTa

ELISAa

qRT-PCR

  

0 dpv

14 dpv

0 dpc

7 dpc

14 dpc

21 dpc

0 dpv

14 dpv

0 dpc

7 dpc

14 dpc

21 dpc

tissue

S01

vac

< 5

17

12

10

10

7

91.6

51.5

53.4

59.6

56.5

53.5

-

S02

vac

< 5

56

24

14

10

14

92.0

45.8

54.9

55.1

65.6

70.2

-

S03

vac

< 5

12

7

6

7

14

97.1

50.8

60.1

64.7

51.3

50.1

-

S04

vac

< 5

< 5

< 5

7

7

7

84.4

33.0

42.4

46.0

51.8

56.6

-

S05

vac

< 5

20

28

14

12

12

92.8

47.5

54.7

57.3

54.6

88.4

-

S06

co

ND

ND

< 5

14

67

40

ND

ND

92.5

42.5

26.9

26.5

+

S07

co

< 5

< 5

< 5

12

375

266

94.9

89.6

94.8

43.8

14.6

17.5

+

S08

co

< 5

< 5

< 5

8

160

67

95.9

86.7

92.0

30.2

30.6

37.9

+

S09

co

< 5

< 5

< 5

10

224

160

99.6

91.0

97.3

44.5

23.1

21.9

+

S10

co

< 5

< 5

< 5

8

56

33

82.4

67.9

73.9

58.8

32.3

27.6

+

  1. Key serological results for vaccinated (vac) and control (co) animals are presented. Serological results are given for 0 and 14 days post vaccination (dpv) to 21 days post challenge infection (dpc). Neutralizing titers (SNT) are given as the reciprocal of the serum dilution showing 50% virus neutralization. Titers of 5 or more were considered positive. ELISA results are calculated as the ratio of the optical density (OD) of the sample and the OD of the negative control (S/N, %). Samples with an S/N value of 40% or less are considered positive. Results for RNA detection are given for tissue samples obtained at autopsy.
  2. aPositive or doubtful ELISA results and positive SNT results are highlighted by bold figures.