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Table 1 Serological results

From: Single immunization with an inactivated vaccine protects sheep from Schmallenberg virus infection

Animal Group SNTa ELISAa qRT-PCR
   0 dpv 14 dpv 0 dpc 7 dpc 14 dpc 21 dpc 0 dpv 14 dpv 0 dpc 7 dpc 14 dpc 21 dpc tissue
S01 vac < 5 17 12 10 10 7 91.6 51.5 53.4 59.6 56.5 53.5 -
S02 vac < 5 56 24 14 10 14 92.0 45.8 54.9 55.1 65.6 70.2 -
S03 vac < 5 12 7 6 7 14 97.1 50.8 60.1 64.7 51.3 50.1 -
S04 vac < 5 < 5 < 5 7 7 7 84.4 33.0 42.4 46.0 51.8 56.6 -
S05 vac < 5 20 28 14 12 12 92.8 47.5 54.7 57.3 54.6 88.4 -
S06 co ND ND < 5 14 67 40 ND ND 92.5 42.5 26.9 26.5 +
S07 co < 5 < 5 < 5 12 375 266 94.9 89.6 94.8 43.8 14.6 17.5 +
S08 co < 5 < 5 < 5 8 160 67 95.9 86.7 92.0 30.2 30.6 37.9 +
S09 co < 5 < 5 < 5 10 224 160 99.6 91.0 97.3 44.5 23.1 21.9 +
S10 co < 5 < 5 < 5 8 56 33 82.4 67.9 73.9 58.8 32.3 27.6 +
  1. Key serological results for vaccinated (vac) and control (co) animals are presented. Serological results are given for 0 and 14 days post vaccination (dpv) to 21 days post challenge infection (dpc). Neutralizing titers (SNT) are given as the reciprocal of the serum dilution showing 50% virus neutralization. Titers of 5 or more were considered positive. ELISA results are calculated as the ratio of the optical density (OD) of the sample and the OD of the negative control (S/N, %). Samples with an S/N value of 40% or less are considered positive. Results for RNA detection are given for tissue samples obtained at autopsy.
  2. aPositive or doubtful ELISA results and positive SNT results are highlighted by bold figures.