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Table 3 Colonization of B. ovis PA and the LPS mutant strains in mouse spleens

From: Mutants in the lipopolysaccharide of Brucella ovis are attenuated and protect against B. ovis infection in mice

B. ovisstrain log10CFU in spleen
3 weeks post infection 10 weeks post infection
mean ± SD mean ± SD Cleared/Totals
B. ovis PA 6.56 ± 0.52 4.67 ± 0.86 0/5
BoΔwadA 6.78 ± 0.40 4.41 ± 2.01 0/5
BoΔwadB 2.31 ± 1.91a 0.80 ± 0.42a 5/5a
BoΔwadC 3.82 ± 0.72a 1.11 ± 0.77a 4/5a
BoΔwadB-revb 5.89 ± 0.77 4.90 ± 0.45 0/5
BoΔwadC-revb 6.49 ± 0.23 4.71 ± 1.68 0/5
  1. Statistical comparison (n = 5) of mean log CFU/spleen or percentage of mice found free from infection in spleens by totals, respectively: aP < 0.005 vs. B. ovis PA; bSibling revertant mutants.