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Table 2 Fecal culture results compared to tissue culture, histology and macroscopy determined at necropsy

From: Shedding patterns of dairy calves experimentally infected with Mycobacterium avium subspecies paratuberculosis

Fecal culture1 Tissue culture2 Histology3 Macroscopy4
0 1 2 3 0 1 2 3 0 1 2 3 4
0 8 9 1 0 6 11 1 0 10 0 2 8 0
1-4 13 13 1 0 2 24 1 0 9 4 0 12 0
> 4 1 1 1 2* 0 1 2 2* 0 0 0 3 2*
  1. Number of calves assigned to each category; 50 in total. Calves in total were experimentally inoculated with MAP.
  2. 1Number of fecal culture-positive samplings starting 2 weeks after inoculation until necropsy.
  3. 20 = no tissue locations culture-positive; 1 = 1–3 tissue locations culture-positive; 2 = 4–6 tissue locations culture-positive; 3 = > 6 tissues culture-positive.
  4. 30 = no lesions; 1 = focal lesions; 2 = multifocal lesions; 3 = diffuse lymphocytic, multibacillary or intermediate lesions.
  5. 40 = no macroscopic changes; 1 = one enlarged or edematous lymph node of the small intestine or liver; 2 = multiple enlarged and edematous mesenteric lymph nodes and/or hyperemia of the ileocaecal valve; 3 = enlarged mesenteric lymph node(s) and/or mild to moderate thickening of ileal or jejunal mucosa; 4 = enlarged mesenteric lymph node(s) and severe thickening and corrugation of the ileal, jejunal and colon mucosa.
  6. *These 2 calves had clinical signs of JD and were euthanized at 16 months of age.