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Table 1 Comparison of xenodiagnosis, initial conventional serology, multiplex serology, and IFNγ ELISpot assays

From: Frequency of IFNγ-producing T cells correlates with seroreactivity and activated T cells during canine Trypanosoma cruzi infection

Dog ID# Xenodiagnosis Initial serology Multiplex serology IFNγ ELISpot SFU
Non-responders
160 - - 0 0
163 - - 0 0
280 - - 0 0
281 - - 0 0
283 - - 0 3
187 n.d. - 0 0
258 n.d. - 0 0
259 n.d. - 0 0
267 n.d. - 0 0
198 n.d. + 0 0
200 n.d. + 0 0
588 n.d. discordant 1 0
260 n.d. n.d. 0 0
B n.d. n.d. 0 0
D n.d. n.d. 0 0
F n.d. n.d. 0 0
I n.d. n.d. 0 n.d.
J n.d. n.d. 0 0
K n.d. n.d. 0 3
L n.d. n.d. 0 0
M n.d. n.d. 0 0
    0/21 0/20
Responders
152 - + 6 400
71 + + 5 55
154 + + 3 108
157 + + 5 13 (-)
159 + + 3 290
266 + n.d. 3 55
272 + + 2 50
274 + + 2 68
276 + + 4 363
284 + + 3 955
43 n.d. + 4 233
67 n.d. + 1 80
69 n.d. + 5 550
193 n.d. + 4 130
197 n.d. + 2 63
434 n.d. + 5 58
572 n.d. + 4 n.d.
573 n.d. + 3 398
589 n.d. + 4 33
P n.d. n.d. 3 823
O n.d. n.d. 5 520
    20/21 19/20
Controls (US)
1 n.d. n.d. 0 0
2 n.d. n.d. 0 3
3 n.d. n.d. 0 0
4 n.d. n.d. 0 n.d.
5 n.d. n.d. 0 n.d.
6 n.d. n.d. 0 n.d.
7 n.d. n.d. 0 n.d.
8 n.d. n.d. 0 n.d.
    0/8 0/3
  1. Forty-two samples from dogs living in a T. cruzi-endemic region are grouped as non-responders and responders based on reactivity to T. cruzi lysate in serological and effector function assays. Test reactivity is annotated as positive (+), negative (-), discordant (disc), or not determined (n.d.). Controls are canine samples from dogs living in the United States. Bold data are results presented as # positive individuals/# total individuals of the groups.