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Table 1 Comparison of xenodiagnosis, initial conventional serology, multiplex serology, and IFNγ ELISpot assays

From: Frequency of IFNγ-producing T cells correlates with seroreactivity and activated T cells during canine Trypanosoma cruzi infection

Dog ID#

Xenodiagnosis

Initial serology

Multiplex serology

IFNγ ELISpot SFU

Non-responders

160

-

-

0

0

163

-

-

0

0

280

-

-

0

0

281

-

-

0

0

283

-

-

0

3

187

n.d.

-

0

0

258

n.d.

-

0

0

259

n.d.

-

0

0

267

n.d.

-

0

0

198

n.d.

+

0

0

200

n.d.

+

0

0

588

n.d.

discordant

1

0

260

n.d.

n.d.

0

0

B

n.d.

n.d.

0

0

D

n.d.

n.d.

0

0

F

n.d.

n.d.

0

0

I

n.d.

n.d.

0

n.d.

J

n.d.

n.d.

0

0

K

n.d.

n.d.

0

3

L

n.d.

n.d.

0

0

M

n.d.

n.d.

0

0

   

0/21

0/20

Responders

152

-

+

6

400

71

+

+

5

55

154

+

+

3

108

157

+

+

5

13 (-)

159

+

+

3

290

266

+

n.d.

3

55

272

+

+

2

50

274

+

+

2

68

276

+

+

4

363

284

+

+

3

955

43

n.d.

+

4

233

67

n.d.

+

1

80

69

n.d.

+

5

550

193

n.d.

+

4

130

197

n.d.

+

2

63

434

n.d.

+

5

58

572

n.d.

+

4

n.d.

573

n.d.

+

3

398

589

n.d.

+

4

33

P

n.d.

n.d.

3

823

O

n.d.

n.d.

5

520

   

20/21

19/20

Controls (US)

1

n.d.

n.d.

0

0

2

n.d.

n.d.

0

3

3

n.d.

n.d.

0

0

4

n.d.

n.d.

0

n.d.

5

n.d.

n.d.

0

n.d.

6

n.d.

n.d.

0

n.d.

7

n.d.

n.d.

0

n.d.

8

n.d.

n.d.

0

n.d.

   

0/8

0/3

  1. Forty-two samples from dogs living in a T. cruzi-endemic region are grouped as non-responders and responders based on reactivity to T. cruzi lysate in serological and effector function assays. Test reactivity is annotated as positive (+), negative (-), discordant (disc), or not determined (n.d.). Controls are canine samples from dogs living in the United States. Bold data are results presented as # positive individuals/# total individuals of the groups.