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Figure 3 | Veterinary Research

Figure 3

From: Npro of classical swine fever virus contributes to pathogenicity in pigs by preventing type I interferon induction at local replication sites

Figure 3

Leucocyte and platelet counts in pigs inoculated with the GPE--derived viruses and with vEy-37. Groups of 5 pigs were inoculated with the indicated viruses and blood was collected on days 0, 3, 5, 7, 9, 11 and 14 pi. The leucocyte (A) and platelet (B) counts were determined for each time point and are shown as mean values with error bars representing the standard deviation. The statistical significance of the differences between the cell counts was calculated using the Student’s t test. * indicates p < 0.05 between vGPE- and vGPE-/N136D. ‡ indicates p < 0.05 between vGPE-/N136D and vEy-37. # indicates p < 0.05 between vGPE-/T830A; V2475A; A2563V and vGPE-/N136D; T830A; V2475A; A2563V. Two pigs inoculated with the vEy-37 virus died on day 7 pi (indicated by †). All remaining pigs were euthanized on day 14 pi.

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