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Table 1 Haplotype distribution in the Greek goats tested (872 chromosomes examined) 1

From: Perspectives of a scrapie resistance breeding scheme targeting Q211, S146 and K222 caprine PRNP alleles in Greek goats

 

PRNP codon number

  

Haplotype

102

110

127

142

143

146

151

154

168

173

211

218

222

240

Haplotype No.

Frequency %

S 240

             

S

147

16.9

G 102 S 240

G

            

S

19

2.2

P 110 S 240

 

P

           

S

37

4.2

S 127 P 240

  

S

          

P

19

2.2

M 142 P 240

   

M

         

P

13

1.5

R 143 P 240

    

R

        

P

4

0.5

D 146 P 240

     

D

       

P

4

0.5

S 146 P 240

     

S

       

P

26

3.0

H 151 S 240

      

H

      

S

1

0.1

H 154 P 240

       

H

     

P

3

0.3

H 154 S 240

       

H

     

S

13

1.5

Q 168 P 240

        

Q

    

P

15

1.7

N 173 P 240

         

N

   

P

2

0.2

Q 211 S 240

          

Q

  

S

52

6.0

L 218 S 240

           

L

 

S

1

0.1

K 222 S 240

            

K

S

49

5.6

P 240

             

P

467

53.6

              

Total

872

100.0

  1. 1The PRNP coding region of 436 healthy Greek goats included in this study was analyzed by DNA sequencing, as described in the main text. Haplotypes were determined through TA cloning of double heterozygous samples. Haplotype frequencies in the tested population are shown.
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Veterinary Research

ISSN: 1297-9716