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Figure 4 | Veterinary Research

Figure 4

From: Ovine and murine T cell epitopes from the non-structural protein 1 (NS1) of bluetongue virus serotype 8 (BTV-8) are shared among viral serotypes

Figure 4

Sheep PBL responses to NS1 predicted peptides. PBLs from sheep infected experimentally with BTV-8 were cultured for 48 h with NS1 peptides and specific IFN-γ response was measured using an ELISPOT assay. Peptide NS1(141) and NS1(522) showed specific IFN-γ production in 7 out of 8 sheep. Peptide NS1(166) II showed specific IFN-γ production in 5 out of 8 sheep. Data are presented as the mean number ± SD of IFN-γ-producing cells in response to stimuli in 8 sheep. *p < 0.05 and **p < 0.01 Mann Whitney test NS1 peptide group vs control.

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