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Table 1 Vaccine groups for challenge study

From: Recombinant adenovirus expressing the haemagglutinin of peste des petits ruminants virus (PPRV) protects goats against challenge with pathogenic virus; a DIVA vaccine for PPR

Group

No goats

Ad-GFP

Ad-H

Ad-IL-2

Ad-GMCSF

A

4

1 × 109 IU

-

1 × 109 IU

1 × 109 IU

B

3

2 × 109 IU

1 × 109 IU

-

-

C

3

1 × 109 IU

1 × 109 IU

1 × 109 IU

-

D

3

1 × 109 IU

1 × 109 IU

-

1 × 109 IU

E

3

-

1 × 109 IU

1 × 109 IU

1 × 109 IU

  1. 16 outbred, European, male goats, 9 to 12 months of age were vaccinated intra-muscularly with a total of 3 × 109 IU of recombinant adenovirus per animal in a final volume of 1 mL PBS.
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Veterinary Research

ISSN: 1297-9716