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Table 2 The relationship between clinical signs, post-mortem lesions, recoveries of APEC strain χ 7122nal R from lung and liver and splenocyte proliferation in response to χ 7122nal R soluble antigen in the first 14 dpi

From: Analysis of immune responses induced by avian pathogenic Escherichia coli infection in turkeys and their association with resistance to homologous re-challenge

Parameter Dpi
  Day 1 Day 3 Day 5 Day 7 Day 14
  Bird number Bird number Bird number Bird number Bird number
  1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Clinical signs1 + + + + + - - - - - - - - - - - - - - - - - - - -
Post-mortem lesions2 + + + + + + + + + + + + + - - + - - - - - - - - -
Log10CFU APEC                          
 Lung 8.9 7.6 7.2 7.5 7.6 6.1 5.2 4.2 5.1 6.8 5.3 4.2 6.4 5.4 5.3 5.2 4.2 7.0 5.8 5.6 0 0 0 0 0
 Liver 8.3 7.1 6.5 5.9 6.1 4.7 4.2 1.0* 1.0* 1.0* 4.2 1.0* 4.5 1.0* 0 3.2 3.3 1.0* 0 0 0 0 0 0 0
Splenocyte proliferation3 - - - - - - - - - - - - - - + a - - - + a + a + b + b + b + b + b
  1. 1Depression, ruffled feathers, hunched posture.
  2. 2Airsacculitis, pericarditis, perihepatitis, fibrin on serosal surfaces; + = presence any of the clinical or pathological signs; - = absence of any observable clinical or pathological signs. None of these clinical signs or post-mortem lesions was seen in the control group of birds given sterile saline.
  3. 3Splenocyte proliferation, - = no response; +a = counts between 200–250 cpm; +b = counts ≥ 2000 cpm.
  4. Bacterial recoveries from lung and liver are given as log10CFU. * = denotes a theoretical value of bacteria obtained after enrichment.