Veterinary Research

Table 5 Chemokine receptor, CD62L and CD163 expression in lungs from control and APP-infected pigs.

From: Distribution of porcine monocytes in different lymphoid tissues and the lungs during experimental Actinobacillus pleuropneumoniae infection and the role of chemokines

	Lungs						Tracheobronchial LN
	Control			APP-infected (necrotic)			Control			APP-infected
CCR1	0.260	±	0.021	5.462	±	1.152**	0.091	±	0.014	1.930	±	0.673**
CCR2	0.070	±	0.009	0.087	±	0.015	0.076	±	0.008	0.174	±	0.029*
CCR3	0.163	±	0.018	2.574	±	0.594**	0.198	±	0.055	0.738	±	0.158**
CCR4	0.054	±	0.013	0.494	±	0.180*	0.333	±	0.058	0.244	±	0.055
CCR5	0.189	±	0.016	0.324	±	0.071	0.085	±	0.007	0.175	±	0.052
CCR6	n.d.			n.d.			n.d.			n.d.
CCR7	0.055	±	0.010	0.094	±	0.021	1.748	±	0.215	1.386	±	0.293
CCR9	0.051	±	0.007	0.030	±	0.004*	0.181	±	0.014	0.130	±	0.015
CCR10	0.021	±	0.002	1.205	±	0.411**	0.015	±	0.002	0.021	±	0.003
CXCR3	0.206	±	0.034	0.719	±	0.255	0.550	±	0.044	0.290	±	0.047**
CXCR4	0.792	±	0.132	1.798	±	0.296**	0.825	±	0.052	2.628	±	0.328**
CXCR6	0.157	±	0.029	0.047	±	0.011**	0.100	±	0.013	0.083	±	0.015
CX3CR1	0.338	±	0.038	0.704	±	0.252	0.115	±	0.012	0.101	±	0.017
CD62L	0.83	±	0.08	35.55	±	9.82**	3.75	±	0.202	13.21	±	2.618**
CD163	1.54	±	0.11	5.85	±	1.20**	1.67	±	0.507	14.81	±	2.561**

The data are shown as a fold change of chemokine receptor, CD62L and CD163 gene mRNA expression in relation to the reference gene HPRT as measured by the RT-qPCR. Data are expressed as mean ± S.E.M. (Control: n = 6, APP-infected: n = 9). The significant differences (Mann–Whitney U test) between control and APP-infected pigs are marked with *P < 0.05, **P < 0.01. The values which were elevated between control and APP-infected pigs are highlighted in bold. LN, lymph node; n.d, non-detected.

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