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Table 5 Chemokine receptor, CD62L and CD163 expression in lungs from control and APP-infected pigs.

From: Distribution of porcine monocytes in different lymphoid tissues and the lungs during experimental Actinobacillus pleuropneumoniae infection and the role of chemokines

  Lungs Tracheobronchial LN
  Control APP-infected (necrotic) Control APP-infected
CCR1 0.260 ± 0.021 5.462 ± 1.152** 0.091 ± 0.014 1.930 ± 0.673**
CCR2 0.070 ± 0.009 0.087 ± 0.015 0.076 ± 0.008 0.174 ± 0.029*
CCR3 0.163 ± 0.018 2.574 ± 0.594** 0.198 ± 0.055 0.738 ± 0.158**
CCR4 0.054 ± 0.013 0.494 ± 0.180* 0.333 ± 0.058 0.244 ± 0.055
CCR5 0.189 ± 0.016 0.324 ± 0.071 0.085 ± 0.007 0.175 ± 0.052
CCR6 n.d. n.d. n.d. n.d.
CCR7 0.055 ± 0.010 0.094 ± 0.021 1.748 ± 0.215 1.386 ± 0.293
CCR9 0.051 ± 0.007 0.030 ± 0.004* 0.181 ± 0.014 0.130 ± 0.015
CCR10 0.021 ± 0.002 1.205 ± 0.411** 0.015 ± 0.002 0.021 ± 0.003
CXCR3 0.206 ± 0.034 0.719 ± 0.255 0.550 ± 0.044 0.290 ± 0.047**
CXCR4 0.792 ± 0.132 1.798 ± 0.296** 0.825 ± 0.052 2.628 ± 0.328**
CXCR6 0.157 ± 0.029 0.047 ± 0.011** 0.100 ± 0.013 0.083 ± 0.015
CX3CR1 0.338 ± 0.038 0.704 ± 0.252 0.115 ± 0.012 0.101 ± 0.017
CD62L 0.83 ± 0.08 35.55 ± 9.82** 3.75 ± 0.202 13.21 ± 2.618**
CD163 1.54 ± 0.11 5.85 ± 1.20** 1.67 ± 0.507 14.81 ± 2.561**
  1. The data are shown as a fold change of chemokine receptor, CD62L and CD163 gene mRNA expression in relation to the reference gene HPRT as measured by the RT-qPCR. Data are expressed as mean ± S.E.M. (Control: n = 6, APP-infected: n = 9). The significant differences (Mann–Whitney U test) between control and APP-infected pigs are marked with *P < 0.05, **P < 0.01. The values which were elevated between control and APP-infected pigs are highlighted in bold. LN, lymph node; n.d, non-detected.