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Table 4 Chemokine receptor, CD62L, CD163 and TBP1 expression by bone marrow and peripheral blood CD163 + monocytes from control and APP-infected pigs.

From: Distribution of porcine monocytes in different lymphoid tissues and the lungs during experimental Actinobacillus pleuropneumoniae infection and the role of chemokines

  Bone marrow Peripheral blood
  Control APP-infected Control APP-infected
CCR1 0.87 ± 0.12 * 0.47 ± 0.07 * 0.87 ± 0.13 1.09 ± 0.30
CCR2 0.35 ± 0.07 * 0.18 ± 0.02 * 0.23 ± 0.08 0.11 ± 0.03
CCR3 4.42 ± 1.00 *† 1.86 ± 0.62 *‡ 18.79 ± 4.77 † 9.21 ± 4.28 ‡
CCR4 3.24 ± 0.71 *† 1.33 ± 0.41 *‡ 13.44 ± 3.25 † 6.42 ± 3.00 ‡
CCR5 0.16 ± 0.03 * 0.06 ± 0.01 *‡ 0.30 ± 0.05 0.15 ± 0.05 ‡
CCR6 n.d. n.d. n.d. n.d.
CCR7 0.46 ± 0.12 † 0.26 ± 0.05 0.88 ± 0.17 0 0.24 ± 0.10 0
CCR9 0.003 ± 0.001 0.001 ± 0.000 0.006 ± 0.002 0 0.001 ± 0.000 0
CCR10 2.62 ± 0.54 *† 1.09 ± 0.31 *‡ 10.54 ± 2.26 0 4.86 ± 2.00 0
CXCR3 2.55 ± 0.55 *† 1.00 ± 0.29 *‡ 10.83 ± 2.58 † 5.10 ± 2.27 ‡
CXCR4 3.81 ± 0.38 *† 2.04 ± 0.15 *‡ 8.70 ± 0.68 † 9.05 ± 1.82 ‡
CXCR6 0.002 ± 0.001 *† 0.000 ± 0.000 * 0.019 ± 0.008 0 0.001 ± 0.000 0
CX3CR1 2.96 ± 0.63 † 1.18 ± 0.31 ‡ 13.01 ± 3.05 † 6.33 ± 2.33 ‡
CD62L 0.81 ± 0.20 0.86 ± 0.21 0.77 ± 0.32 1.29 ± 0.27
CD163 5.31 ± 0.52 *† 9.08 ± 2.27 *‡ 11.98 ± 2.55 † 19.40 ± 2.43 ‡
SLA-DR 16.62 ± 2.77 *† 4.43 ± 0.76 * 40.60 ± 4.04 0 4.23 ± 1.23 0
TBP1 0.06 ± 0.01 0.06 ± 0.01 0.09 ± 0.02 0.11 ± 0.02
  1. The data are shown as a fold change of chemokine receptor, CD62L, CD163, SLA-DR and TBP1 reference gene mRNA expression in relation to the reference gene HPRT as measured by the RT-qPCR. Data are expressed as mean ± S.E.M. (n = 5). The significant differences (Mann-Whitey U test, P < 0.05,) between control and APP-infected pigs are marked with * (bone marrow) or 0 (peripheral blood). The significant differences (Mann–Whitney U test, P < 0.05) between bone marrow and peripheral blood monocytes are marked with † (control) or ‡ (APP-infected). The values which were elevated between control and APP-infected pigs are highlighted in bold. N.d, non-detected.