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Table 2 Monocyte subpopulations in various body compartments from control and APP-infected pigs.

From: Distribution of porcine monocytes in different lymphoid tissues and the lungs during experimental Actinobacillus pleuropneumoniae infection and the role of chemokines

   CD163- CD163+ % CD163+
n Control APP-infected Control APP-infected Control APP-infected
Bone marrow 5 1571 ± 118 464 ± 83** 1020 ± 161 1430 ± 142 38.6 ± 2.7 75.2 ± 4.3**
Peripheral blood 5 418 ± 61 184 ± 44* 418 ± 111 1142 ± 255* 47.1 ± 6.9 86.2 ± 0.5**
Spleen 4 3009 ± 916 1052 ± 273* 3524 ± 1,043 10 886 ± 3359 54.8 ± 9.6 90.0 ± 1.8*
Lungs Unaffected area 5 1459 ± 336 735 ± 225* 3384 ± 702 7555 ± 1493* 69.0 ± 7.4 90.9 ± 2.1**
Demarcation zone 4   985 ± 467   11 890 ± 4331   90.4 ± 3.8*
Necrotic area 5   2873 ± 1,441   5948 ± 2232   66.2 ± 6.0
Tracheobronchial LN 5 n.d. 1547 ± 674* n.d. 16 563 ± 4284* n.d. 92.9 ± 1.7
Mesenteric LN 4 n.d. n.d. n.d. n.d. n.d. n.d.
  1. The data are shown as total count × 103 of monocyte subpopulations per g of tissue of per mL of PB or as a percentage of CD163+ monocytes from CD163+ and CD163- monocytes as measured by flow cytometry. Data are expressed as mean ± S.E.M. The significant differences (Mann–Whitney U test) between control and APP-infected pigs are marked with *P < 0.05, **P < 0.01. The values which were elevated between control and APP-infected pigs are highlighted in bold. LN, lymph node, n.d, non-detected.