Macroscopic lesions* | Control | Low dose | High dose |
---|
2 weeks | 3 months | 6 months | 9 months | 12 months | 2 weeks | 3 months | 6 months | 9 months | 12 months |
---|
0 | 6 | 1 | 1 | 3 | 5 | 2 | Â | 1 | 2 | 3 | 1 |
1 | Â | 1 | 1 | 1 | Â | Â | Â | Â | 1 | Â | Â |
2 | Â | Â | 1 | Â | Â | Â | 1 | Â | Â | Â | Â |
3 | Â | 3 | 2 | 1 | Â | 3 | 2 | 4 | 2 | 2 | 4 |
4 | Â | Â | Â | Â | Â | Â | 2 | Â | Â | Â | Â |
- *0 = no macroscopic changes; 1 = one enlarged or edematous lymph node of the small intestine or liver; 2 = multiple enlarged and edematous mesenteric lymph nodes and/or hyperemia of the ileocaecal valve; 3 = enlarged mesenteric lymph node(s) and/or mild to moderate thickening of ileal or jejunal mucosa; 4 = enlarged mesenteric lymph node(s) and severe thickening and corrugation of the ileal, jejunal and colon mucosa.