Figure 7From: H3N2 canine influenza virus causes severe morbidity in dogs with induction of genes related to inflammation and apoptosisMicroarray analysis of genes associated with dendritic cells and antigen presentation, apoptosis, Th1 and Th2 CD4+T lymphocytes. The mRNA from the left cranial lobes of the lungs from dogs (Korean mongrel, n = 3) infected with A/Korea/S1/Canine/2012 (H3N2) and from PBS mock-infected dogs were subjected to microarray analysis. The genes induced higher in the infected dogs were quantified by real-time PCR. A, Heat map of genes related to dendritic cells (DC) and antigen presentation (APC); B, Heat map of genes related to apoptosis; C, Heat map of genes related to Th1 CD4+ T lymphocytes; D, Heat map of genes related to Th2 CD4+ T lymphocytes; E, Microarray data of dendritic cells and antigen presentation, apoptosis, Th1 and Th2 CD4+ T lymphocytes; F, mRNA fold changes of selected genes of dendritic cells and antigen presentation, apoptosis, Th1 and Th2 CD4+ T lymphocytes.Back to article page