Emergence of a new lagovirus related to Rabbit Haemorrhagic Disease Virus

Table 2 Mortality results following experimental challenges with 4 RHDV2 or 1 RHDV reference strains.

Study	Rabbit origin	Administration route	Inoculum strain	Mortality	Seropositivity of the survivors (doubtful)²	Mortality 2nd challenge RHDV BS89
A ¹	NZ	IM	10-07	1/5	/
A ¹		IM	V/RHD/4	3/5	/
B ¹	NZ	oral	10-28	6/8	/
C	NZ	IM	10-28	1/2	1/1
C		oral	10-28	2/2	/
D	NZ	oral	10-28	3/9	6/6
E	NZ	oral	10-28	0/5	5/5
F	NZ	oral	Ud11	1/5	4/4	0/4³
G ¹	NZ	oral	10-32	0/8	/
G ¹		oral	V/RHD/4	8/8	/
H	NZ	oral	10-32	0/3	3/3
I	NZ	IV	10-32	0/4	4/4	0/1³
I		oral	10-32	1/6	5/5	2/4³
J	NZ	oral	10-32	2/5	3/3
K	NZ	oral	10-32	0/5	4(1)/5
L	NZ	oral	10-32	0/5	5/5	0/4³
	Rural	oral	10-32	0/5	5/5	1/5

The experimental challenges were performed with RHDV2 strains 10–07, 10–28, 10–32, and Ud11, or with the French RHDV reference strain V/RHD/4, using different inoculation routes. For experiments F, I, and L, mortality results following a second challenge with the Italian RHDV reference strain BS89 of the survivor rabbits are shown.
NZ New Zealand, IM intramuscularly route, IV intravenous route.
¹no serological data.
²doubtful because just above the threshold.
³the 2nd challenge was performed on a part of the survivor rabbits.

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